Naproxen: What It Is, How to Use It, and What to Watch For

If you’ve ever needed a strong over‑the‑counter painkiller, you might have seen naproxen on the shelf. It’s an anti‑inflammatory drug that can calm aches from headaches, muscle strains, arthritis, and more. In this guide we’ll break down how it works, the best way to take it, and what side effects you should know.

How Naproxen Works and When to Take It

Naproxen blocks chemicals called prostaglandins that cause pain and swelling. Because it stays in your system longer than ibuprofen, you usually only need a dose every 8‑12 hours. That makes it handy for chronic conditions like osteoarthritis where you want steady relief.

Typical adult dosing is 250 mg to 500 mg taken twice daily with food. If you’re using the lower 220 mg OTC tablets, two tablets at once equal about 440 mg, which is within the safe range for most people.

Common Side Effects and Safety Tips

The good news is many people tolerate naproxen well, but it can upset your stomach. Taking it with a meal or a glass of milk helps reduce nausea and heartburn. If you notice ringing in the ears, severe stomach pain, or black stools, stop using it and call a doctor right away.

People with a history of ulcers, kidney problems, or heart disease should talk to their healthcare provider before starting naproxen. It can raise blood pressure, so check your numbers regularly if you’re on it for a long time.

Alcohol can make stomach irritation worse, so keep drinking low while you’re on naprof​en. Also, avoid mixing it with other NSAIDs like ibuprofen or aspirin unless your doctor says it’s safe.

If you miss a dose, take it as soon as you remember—unless it’s almost time for the next one. Don’t double up; extra doses won’t make pain disappear faster but could increase side‑effect risk.

For kids under 12, naproxen isn’t recommended without pediatric guidance. There are other safer options for younger children.

When you finish a course of naproxen, don’t suddenly stop if you’ve been using it daily for weeks. Talk to your doctor about tapering down to avoid rebound pain.

Overall, naproxen is a solid choice for moderate to severe pain when you need longer‑lasting relief. Follow the dosing instructions, watch for stomach issues, and keep your doctor in the loop if you have any health concerns.